Morphine-associated pruritus after single extradural administration in a horse


      Pruritus following a single administration of 100 μg kg−1 of preservative-free morphine sulphate given via an extradural catheter was seen in a 580 kg horse. The catheter was placed in the first intercoccygeal space. Focal irritation, represented by both local alopecia over the left gluteal muscles and serum exudation, occurred 4–8 hours after injection. This was attributed to the extradural morphine administration.


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